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New Brief Description: Background: Tobacco use, particularly cigarette smoking, is a leading lifestyle-related cause of death in the United States. HIV-positive individuals who smoke experience higher morbidity and mortality compared to HIV-positive...
This Funding Opportunity Announcement (FOA) will support research grants to address urgent, time-sensitive research questions on the relationships between alcohol consumption and COVID-19 related outcomes and consequences. The principal area of focus is research that can improve public health in the near term by informing responses to the current COVID-19 pandemic, in view of 1) the impact of alcohol misuse on incidence and severity of COVID-19 disease or 2) the effect of the COVID-19 disease and pandemic-induced restrictions on alcohol use and alcohol use disorder (AUD).
New Brief Description: Background: Tobacco use, particularly cigarette smoking, is a leading lifestyle-related cause of death in the United States. HIV-positive individuals who smoke experience higher morbidity and mortality compared to HIV-positive.
The purpose of this Notice is to encourage grant applications proposing research that makes use of available, large data sets with the objective of improving HIV epidemic modeling and service planning, with attention to greater attention to the role of substance use. Data may be from NIDA-funded or co-funded projects as well as from other sources.
The purpose of this funding opportunity is to develop technologies to improve the delivery of pharmacological, gene editing, or other cargoes for HIV and SUD mechanistic research.
NIMH is issuing this Notice to highlight interest in research applications to optimize health communication strategies that advance HIV prevention, treatment and cure. Health communication science has made pivotal contributions to HIV prevention and treatment efforts. Early media campaigns that promoted condom use and HIV testing, proved to be positive influences on knowledge, attitudes and social norms. Increased use of client-centered communication in HIV treatment settings, contributed to greater antiretroviral therapy (ART) adherence and retention in care.
This initiative will support (1) observational research to understand the role of structural racism and discrimination (SRD) in causing and sustaining health disparities, and (2) intervention research that addresses SRD in order to improve minority health or reduce health disparities.
The goal of this Notice of Special Interest [NOSI] is to support research that will define and validate a set(s) of molecular biomarkers and/or bio-signatures indicating the degree of loss of functional reserve, or of resilience of the host defense mechanisms in people with substance use disorders (SUDs) who acquired HIV (PWH) and are on antiretroviral therapy (ART).
The shock and kill strategy is one of the commonly used approaches for targeting latent reservoirs in hopes to cure HIV-1. It is based on the concept of purposely inducing reactivation of latent reservoirs in ART (antiretroviral therapy)-treated individuals by using stimulatory agents. However, it has become increasingly evident that attempts at elimination of HIV-1 reservoirs through latency reactivating agents (LRA) -mediated reactivation alone may not be sufficient.
This Funding Opportunity Announcement (FOA) invites applications for investigator-initiated clinical trials of complementary and integrative health approaches with physical and/or psychological therapeutic inputs (often called mind and body interventions) in NCCIH-designated areas of high research priority.
