The OAR develops an annual Trans-NIH Plan for HIV-Related Research (Strategic Plan) to ensure that the Trans-NIH AIDS research budget is used to fund the overarching HIV/AIDS research priorities. It provides a roadmap for the NIH HIV/AIDS research effort, which is carried out by nearly all of the NIH Institutes and Centers. The Plan shapes the NIH investment in building on the most recent scientific progress and opportunities to develop a safe and effective AIDS vaccine, generate a cure for HIV/AIDS, and ultimately achieve an AIDS-free generation and an end to the AIDS pandemic. The Plan also serves as a resource to inform the public, the scientific community, Congress, and the AIDS-affected communities about the NIH HIV/AIDS research agenda. It is developed through a collaborative process involving broad input from NIH intramural and extramural scientists and other U.S. and internationally based stakeholders.