William E. Paul, M.D.
William E. Paul, M.D., a leading immunologist, well known for his discovery of interleukin-4 (IL-4) and for an extensive body of research that includes the purification of IL-4, the characterization of its receptor and its signaling mechanisms, served as the Director of the Office of AIDS Research from February 1994 until October 1997. Under Dr. Paul’s leadership, the office implemented new broad authorities provided by the NIH Revitalization Act of 1993 to expand the role of OAR in determining national AIDS research policy. During his tenure, the OAR developed the first annual comprehensive plan and unified budget for all NIH-sponsored AIDS scientific activities. Dr. Paul, who also headed the Laboratory of Immunology at the National Institute of Allergy and Infectious Diseases, left the directorship to return full-time to his lab, redirecting his scientific efforts to searching for a safe and effective HIV vaccine and for new approaches to vaccine development in general. Dr. Paul is a member of the U.S. National Academy of Science and of its Institute of Medicine. He is a fellow of the American Academy of Arts and Sciences.